10 Best Melatonin Supplements for Sleep Regulation

According to the CDC, about 32.8% of adults don’t get enough sleep—meaning nearly one-third of the population is sleep-deprived every day. Poor sleep can lead to a range of physical and mental health, from lack of focus to immune system disruptions.

In this context, melatonin supplements are becoming increasingly popular as a way to support the body’s natural sleep-wake cycle, promoting more restful sleep." to stay compliant. If you're looking for a solution that’s effective, safe, and fits your personal needs, explore our curated list of the best melatonin supplements worth considering below.

Comparison Table of the 10 Best Melatonin Supplements for Better Sleep Quality

How Do We Choose the Best Melatonin Supplements?

Brand Reputation

A trustworthy brand is a key factor when choosing a melatonin supplement. Reputable companies tend to receive positive reviews from users and strictly follow quality manufacturing standards.

Look for well-established brands that are transparent about their product information and consistently get good feedback on platforms like Amazon, iHerb, or health-focused communities. This helps ensure the product you choose is both safe and effective in supporting sleep regulation.

Ingredients Quality

The purer the melatonin, the better it can support your sleep. When shopping, check the product label carefully to ensure the melatonin dosage is clearly listed and that it doesn’t contain unnecessary additives like artificial coloring, flavors, or fillers.

Some supplements also combine melatonin with other sleep-supporting ingredients such as L-theanine, licorice, or chamomile extract. When blended properly, these can boost overall effectiveness. However, transparency in sourcing and third-party testing should always remain top priorities.

Form and Dosage

Melatonin supplements come in various forms—capsules, fast-dissolving tablets, gummies, and liquid drops—each suited to different needs and preferences.

Capsules and tablets are odorless, easy to swallow, and ideal for those who want precise dosage control. Fast-dissolving (sublingual) forms absorb quicker, which can benefit people who have trouble falling asleep. Gummies are flavored and chewable, making them an appealing option for older adults or teens.

Doses of melatonin between 1 mg and 6 mg appear to be effective for improving sleep, according to research [1]. Starting with the lowest effective dose is generally recommended to minimize potential side effects and allow your body to adjust.

Regardless of the format, it’s important to follow the recommended dosage to avoid unwanted effects and ensure safe, consistent use.

Manufacturing Standards and Certifications

Melatonin is a hormone, so the purity and production standards of each supplement must be tightly regulated. Choose products manufactured in cGMP-certified facilities, which ensures quality control from raw materials to packaging.

Additional certifications from third-party organizations like NSF or USP, or labels such as “non-GMO” and “gluten-free,” can increase reliability—especially for those with dietary restrictions or allergy concerns. Picking a transparent, certified product helps ensure long-term safety.

Price and Value for Money

Melatonin supplement prices vary widely, typically ranging from $0.2 to $0.8 per dose depending on the form, dosage, and brand. However, higher price doesn’t always mean higher quality, and cheaper options may not save money if the product is poorly absorbed or under-dosed.

To assess true value, consider the total number of servings per bottle, the potency per serving, and any additional ingredients included. A reasonably priced supplement with optimal dosage and clear results is a smart investment in consistent, restful sleep.

Formula

A melatonin supplement is rarely just melatonin. Behind each formula is a careful blend of supportive ingredients designed to help the body relax and ease naturally into sleep—without that groggy feeling in the morning.

Magnesium glycinate is a popular ingredient in many sleep supplements. It's well-absorbed, easy on the stomach, and supports a calm nervous system. When combined with melatonin in sleep formulas, it's often selected for its soothing effects and gentle absorption.

Related article: Melatonin And Magnesium Together For Sleep: Things To Know

L-theanine, an amino acid found in green tea leaves, is a popular addition to sleep formulas. While it doesn’t directly induce drowsiness, it helps promote a calm and relaxed state, creating a more supportive environment for melatonin to take effect.

Other blends may include calming herbs like valerian root, chamomile, or lemon balm. These offer a mild sedative effect, especially helpful for people whose sleep is impacted by stress. However, if the product already contains a moderate to high melatonin dose, combining it with strong herbal sedatives should be done with care to avoid feeling overly sluggish.

In short, instead of choosing high-dose melatonin on its own, there are plenty of thoughtfully crafted formulas that support natural, lasting sleep in a gentler way.

10 Best Melatonin Supplements for Sleep Regulation

OLLY Sleep Gummy 153mg - 60 servings | $ 29.99

Review

OLLY Sleep Gummy is a popular choice thanks to its thoughtful combination of 3mg melatonin, L-theanine, and herbal extracts like chamomile, passionflower, and lemon balm. This product is designed to help users fall asleep faster, enjoy deeper rest, and unwind naturally before bed.

The Blackberry Zen flavor offers a gentle sweetness with a refreshing minty finish, making it pleasant to take. Additionally, it's gluten-free and contains no artificial colors or flavors, making it suitable for people following a clean and healthy lifestyle.

OLLY is committed to product quality, with NSF certification—an independent standard ensuring safety and label accuracy.

With over 80% of customer ratings between 4 and 5 stars and the “Amazon’s Choice” badge, based on anecdotal reviews. Many said they fall asleep within 30 minutes of taking it and experience deeper, more restful sleep.

However, there are mixed reviews about the texture and overall value. Some users found the gummies too soft and prone to losing their shape—especially during shipping in warmer climates. Others felt that the $29.99 price tag for 60 servings may be slightly high compared to similar products.*

Pros

• Amazon’s Choice badge
• NSF certified for quality, safety, and label accuracy
• Eco-friendly packaging that uses less plastic while preserving product quality
• Gluten-free and suitable for a variety of dietary needs

Cons

• Reports of nausea and dizziness in certain users*
• May promote deep sleep but also trigger vivid or unpleasant dreams*

Pure Encapsulations Melatonin 0.5mg - 180 servings | $29.80

Review

Pure Encapsulations Melatonin 0.5 mg is a highly rated option for those looking for a gentle, sustainable sleep support solution.

With a low dose of just 0.5 mg per capsule—enough to help regulate the body’s natural circadian rhythm without overwhelming the system—this product is especially suitable for individuals sensitive to higher melatonin doses or those who want to use it long-term.

One of the reasons users trust this product is the brand's outstanding reputation. Pure Encapsulations has been ranked as the most trusted professional supplement brand for quality and reliability in surveys conducted by the Nutrition Business Journal in 2016, 2020, and 2023.

What sets this product apart is its commitment to purity: it’s free from gluten, GMOs, and common allergens like wheat, dairy, soy, and eggs. It also contains no unnecessary additives such as artificial colors, sweeteners, or preservatives. This makes it an ideal choice for vegetarians or people with sensitivities.

This supplement is designed to align with the body’s internal sleep cues—often referred to as the internal clock—and is manufactured in accordance with cGMP standards. It also undergoes rigorous testing for purity, potency, and ingredient sourcing.

The product’s quality is reflected in real-world user feedback. One user shared:

"Tried the higher doses and always woke up 4 or so hours after going to sleep OR it would work for a few days and stop being effective. Got this and worked like a DREAM, literally.

Sure the price is a bit higher but what price do you put on a good night's sleep? Plus, I’m a firm believer, you get what you pay for. Cheaper ones are higher dosage and lower quality and less effective. This one is the lowest dose and high quality and super effective. No brainer to me!!"* – CMR

With a brand philosophy focused on "good from start to finish," this product not only promotes restful sleep but also supports a healthier lifestyle through sustainability and community wellness initiatives.

Pros

• Certified as Amazon’s Choice based on customer satisfaction and effectiveness
• Free from common allergens including gluten, soy, eggs, dairy, tree nuts, and peanuts—making it friendly for vegetarians and those with sensitivities
• Manufactured under strict cGMP standards, backed by over 50 published studies
• Available in multiple sizes (60 or 180 capsules) to suit both short-term and long-term use

Cons

• Some users reported receiving bottles with minor defects such as misaligned caps or brown spots under the seal*
• Higher price point compared to many other melatonin products on the market*
• A few users experienced side effects like restlessness, increased heart rate, or difficulty falling asleep*

Vinatura Magnesium Complex Sleep Aid 60 Servings | $17.89

Review

Vinatura Magnesium Complex is a natural supplement designed to support relaxation and healthy sleep quality, without next-day grogginess.

Its formula is a well-balanced blend of Magnesium Glycinate (500mg)—a highly absorbable and gentle form of magnesium, Melatonin (5mg)—a hormone that helps regulate the sleep-wake cycle, and L-Theanine (50mg)—an amino acid that promotes deep relaxation.

The synergy of these three ingredients helps relax muscles, calm the nervous system, and support restful, uninterrupted sleep.

Customer CElizab shared: "This supplement is INCREDIBLE! I actually only need to take one capsule, it lights out for me for 8 hours! I wake up refreshed and renewed, ready to take on my day! No grogginess as it’s all natural supplementation!"—highlighting how quickly the supplement promotes sleep and how refreshed users feel upon waking.*

Beyond its effectiveness, the product stands out for its commitment to quality and transparency. Vinatura conducts third-party testing at respected labs to verify purity, eliminate contaminants, and ensure ingredient accuracy.

Manufactured in the USA in a cGMP-certified facility, Vinatura capsules are also free from common allergens such as soy, dairy, and wheat—making them suitable for people with sensitive digestive systems.

Olichka Popovych noted: "This supplement has made a huge difference in my sleep quality. I used to toss and turn for hours, but now I fall asleep much faster and stay asleep longer. The magnesium glycinate feels gentle on my stomach, and the added melatonin is just the right amount."

With over 80% positive customer reviews and the “Amazon’s Choice” label, this supplement has built a strong reputation for trust and effectiveness in promoting quality sleep.

Pros

• Third-party tested by world-renowned labs to verify the purity and potency of all ingredients.
• Made in the USA in a cGMP-certified facility, meeting high standards for safety and quality.
• Labeled “Amazon’s Choice,” reflecting strong customer satisfaction and consistent product performance

Cons

• Requires taking two capsules per serving: Some customers wish the product had a higher concentration so they could take just one capsule instead of two per serving.*

Natrol Fast Dissolve Melatonin 100 servings | $12.52

Review

Natrol Fast Dissolve Melatonin 10mg is a great choice for those seeking a simple and convenient way to support restful sleep—without the use of medications. This product comes in a pleasant strawberry flavor and is easy to use—no water needed—making it ideal for people with busy schedules or frequent travelers.

One major advantage of Natrol’s fast-dissolve tablets is their rapid action. The supplement is designed to support longer, more restful sleep, particularly for adults with occasional sleeplessness. According to Natrol, it helps the body realign its natural sleep cycle, contributing to a more refreshed feeling upon waking.

Beyond its sleep benefits, Natrol is a trusted name among consumers. In a 2022 survey by ConsumerLab.com, Natrol was ranked the number one melatonin brand for consumer satisfaction. The company also emphasizes its commitment to quality, manufacturing its products in facilities that follow strict cGMP standards.

One Amazon user shared the following review:

"I used to buy or get the 3mg one prescribed but it didn’t really work for me so bought these and let me tell you every time I take them I fall asleep in under 30 minutes. I also used to wake up sometimes during the night when using some melatonin that was 3 mg. With this I stay asleep which is what I love about it. My mom use them too and she likes them too"* – Annaïna

Pros

• Labeled as Amazon’s Choice, showing high customer trust and satisfaction
• Drug-free and non-habit forming, ideal for those seeking a safer way to improve sleep
• Pleasant strawberry flavor and fast-dissolving tablet that doesn’t require water—great for on-the-go users
• Manufactured in facilities that comply with strict cGMP quality standards

Cons

• Contains maltodextrin, which may cause sudden blood sugar spikes in sensitive individuals*
• A few users have experienced allergic skin reactions such as rashes*

THORNE Melaton-3 60 servings | $15.00

Review

THORNE Melaton-3 is a great choice for those seeking a natural and gentle solution to improve sleep quality and support the body’s internal clock. Each capsule contains 3mg of melatonin, helping users relax and fall asleep more easily. It is especially helpful for shift workers or those who frequently travel across time zones.

One of the standout features of THORNE Melaton-3 is its clean formulation. It’s free from gluten, dairy, soy, and common allergens such as eggs, shellfish, and tree nuts, making it ideal for people with dietary restrictions or sensitive systems.

Thorne is a brand recognized by many healthcare professionals, elite athletes, and organizations like the U.S. National Teams and Mayo Clinic. The product has also undergone third-party testing to verify label accuracy and ensure it is free from harmful levels of unnecessary heavy metals, pesticides, or microbes.

Highly rated on Amazon and labeled as Amazon’s Choice, this supplement has received positive feedback from users. As one reviewer, rick m, shared:

"I bought these to give me something to take on days when I'm sort of wired and need help going to sleep. I had someone recommend the larger size but I went with the smaller as I didn't want to be too knocked out. These things work - took one over the w/e and slept 9 hours. Was a little groggy in the morning but after breakfast and a shower I felt human again."*

Pros

• Amazon’s Choice certification reflects strong trust and satisfaction among real users
• Third-party tested to confirm label accuracy and absence of harmful contaminants
• Free from common allergens such as gluten, soy, dairy, eggs, shellfish, and tree nuts—great for people with sensitivities
• Thorne is a trusted brand among healthcare professionals, the U.S. National Teams, and Mayo Clinic, offering peace of mind to consumers

Cons

• A few users experienced nightmares after using the supplement*
• Some reports mention discomfort during the night and headaches the following morning*

NOW Foods Liquid Melatonin 68 servings | $5.49

Review

NOW Foods Liquid Melatonin comes from NOW Foods—a long-standing, family-owned American brand that has been in operation since 1968 and is known for producing high-quality dietary supplements.

This product features a liquid melatonin formula delivering 3mg per serving. The liquid form allows for faster absorption and ease of use, ideal for those who prefer alternatives to pills. Beyond supporting sleep, it may also aid in regulating circadian rhythms, and promoting digestive health.

NOW Foods Liquid Melatonin is manufactured in a facility rated A by the Natural Products Association (NPA) under Good Manufacturing Practices (GMP), ensuring strict standards for purity, potency, and safety.

Many users have noted the product’s effectiveness, highlighting the quick absorption of the liquid and its pleasant taste. However, some customers have expressed concerns about the dropper being unclear or lacking measurement markings, which can make accurate dosing more challenging during daily use.*

Pros

• Certified as Amazon’s Choice, reflecting high satisfaction from a broad base of consumers
• Manufactured in an NPA A-rated GMP facility, ensuring tight quality control
• Liquid form allows for fast absorption, ideal for those who struggle with swallowing pills or need quick effects
• Made in the USA by a trusted brand that has operated continuously since 1968

Cons

• Some users find the product overly sweet, which may be unpleasant for those sensitive to taste*
• There are reports that the flavor is more medicinal than “unflavored” as advertised*

ONNIT Melatonin Liquid Spray 30 servings | $12.26

Review

ONNIT Melatonin Liquid Spray is a convenient spray-foam sleep aid from ONNIT, a trusted brand known for transparency, third-party testing, and environmentally friendly certifications. The compact 1 fl oz spray bottle is easy to travel with and contains 3mg of melatonin per serving, making it an ideal companion for those in need of fast and effective sleep support.

The liquid formula allows for rapid absorption, helping the body fall asleep faster and maintain deeper rest throughout the night. It's a suitable option not only for people who experience occasional sleeplessness but also for shift workers and frequent travelers who need help adjusting to new time zones.

The product is lightly sweetened with stevia instead of sugar, and it's gluten-free—making it friendly for those with dietary restrictions.

Many users have praised the product’s effectiveness. For example, Luke shared:

"Onnit is a very reliable company with great products! I have tried a lot of melatonin products (spray, gummies, pills, lotion, etc) . This is the best. I don’t know if the lavender taste is the best as I’ve never tried lavender flavors in other things but the mint is truly divine. If I want to slow down I don’t do the 6 sprays, just two or three."*

Pros

• Gluten-free and sugar-free, sweetened with stevia—suitable for those on special diets or watching their sugar intake.
• Compact spray bottles are travel-friendly and convenient for on-the-go or flexible use.
• Third-party tested for purity and safety, ideal for athletes and those avoiding banned substances.
• Refreshing mint flavor is well-received and considered more pleasant than many other melatonin supplements.

Cons

• Some users reported receiving a version different from what they had previously purchased.*
• There are cases of customers receiving a citrus flavor instead of the advertised mint*
• A few users experienced throat irritation after use, possibly due to sensitivity to the spray format.*

ZzzQuil PURE Zzzs Triple Action Melatonin Gummies 30 serving | $16.79

Review

ZzzQuil PURE Zzzs Triple Action Melatonin Gummies is an over-the-counter sleep support product from Vicks, a globally recognized brand under Procter & Gamble.

This product stands out for its Triple Action formula, featuring 6mg of melatonin (three times more than the original ZzzQuil PURE Zzzs), combined with ashwagandha—an adaptogenic herb known to help ease stress.

The gummies also include a botanical blend with chamomile, lemon balm, valerian root, and lavender, designed to calm the mind and support the body’s natural sleep cycle.

Customers generally praise the product’s effectiveness in helping them fall asleep faster, stay asleep longer, and wake up without grogginess. Around 80% of users left positive feedback, noting that it does not leave them feeling drowsy in the morning.*

However, the taste has received mixed reviews—some enjoy the blackberry vanilla flavor, while others complain about the taste and color. A few users also expressed concern about the use of artificial food coloring, which they said can stain the tongue and teeth.*

Pros

• Contains triple the melatonin dose compared to the regular formula, boosting its sleep support and antioxidant potential.
• Includes ashwagandha, a Ayurvedic herb known for promoting relaxation and reducing stress.
• Drug-free, non-habit forming, gluten-free, lactose-free, and gelatin-free.
• Manufactured by Procter & Gamble, a trusted company with over 180 years of experience and recognized as the No.1 global sleep aid brand (Euromonitor 2023).

Cons

• Some users found the gummy flavor unpleasant and noted that it can leave color stains on the tongue.*
• There were reports of inconsistent quality between different purchases.*
• Although designed to be pleasant, the blackberry vanilla flavor may not appeal to everyone.*

Nature Made Melatonin 90 servings | $11.49

Review

Nature Made Melatonin 5mg is an over-the-counter option formulated to support adults who experience occasional difficulty falling or staying asleep. This product contains melatonin—a natural hormone in the body that helps regulate the sleep cycle—in a small, easy-to-swallow tablet form.

It’s tasteless, non-habit forming, and made without artificial colors or preservatives. Each tablet delivers 5mg of melatonin, helping users fall asleep more easily and enjoy a deeper rest. The recommended dosage is one tablet one hour before bedtime, with a maximum of two tablets per day.

One standout feature is that Nature Made products are verified for quality and potency by the United States Pharmacopeia (USP), an independent organization that sets strict standards for dietary supplements.

Additionally, according to the 2024 U.S. News & World Report and Pharmacy Times Best OTC Products survey, Nature Made was ranked the #1 pharmacist-recommended brand for vitamins and supplements in the U.S.

Customer Buckeye Ninja shared:

“I purchased the 5 mg Melatonin tablets, and they work great. I typically take two tablets 2-3 days a week, about 45-70 minutes before bedtime. Each time, I get a good night’s sleep and wake up feeling well-rested.

However, I wouldn’t recommend going out after taking these, as they might make you feel very tired unexpectedly. The tablets are small, easy to swallow with water, and don’t leave an aftertaste. Be cautious if you spill or drop one on the floor, as they can be difficult to find at times.”*

Pros

• USP-verified for quality, strength, and pharmaceutical-grade manufacturing standards
• Reputable brand—Nature Made is the #1 pharmacist-recommended vitamin and supplement brand in the U.S.
• Non-habit forming, gluten-free, free from preservatives and artificial colors—safe for long-term use

Cons

• Contains Dibasic Calcium Phosphate, which may interact with certain medications if not monitored carefully.*
• Packaging may feel wasteful, as the bottle is large but the tablets only fill the bottom portion.*
• Includes Croscarmellose Sodium, a filler that could cause mild irritation in sensitive individuals.*

BulkSupplements.com Melatonin Powder About 333333 servings - 3mg | $144.97

Review

BulkSupplements.com Melatonin Powder is a solid choice for those looking for a pure melatonin product with flexible dosing and long-term cost efficiency. Packaged in powder form, each serving delivers 3mg of vegan melatonin, free from unnecessary fillers and gluten, making it compatible with a wide range of dietary preferences.

One of its biggest advantages is the powder format, which allows users to easily customize their dosage—a major benefit for those who need lower melatonin doses or are personalizing their supplement routine.

BulkSupplements.com is known for offering over 500 different supplements and emphasizes transparency in every stage of production. All products are manufactured in a facility that complies with strict cGMP standards and are third-party tested for quality, from raw ingredients to finished goods.

Users have praised the product for helping improve sleep and wakefulness. Many report sleeping more soundly and waking up feeling refreshed. The absence of unnecessary fillers also gives users confidence in the purity and potency of each dose.

However, the product may not be easy for everyone to get used to. Some reviewers noted that the powder has a bitter taste and doesn’t dissolve well, making it less convenient to mix and consume.

In addition, accurately measuring doses may be challenging for users unfamiliar with powdered supplements. That said, for those willing to learn how to measure and use it properly, this remains a strong long-term option.

Pros

• Manufactured in a facility that meets strict cGMP standards to ensure safety and product consistency.
• Undergoes third-party quality testing at multiple stages, from raw materials to finished product.
• Pure melatonin with no unnecessary fillers, additives, or artificial flavors
• Highly concentrated powder, available in bulk (up to 1kg), ideal for long-term users or those wanting to customize dosage.

Cons

• Does not include a measuring scoop, which may make it difficult for beginners to measure accurate doses.*
• Powder has a bitter taste and does not dissolve easily in water, leading to an unpleasant experience for some users.*
• Some users may experience mild discomfort or sensitivity to dosage.

Conclusion

Quality sleep plays a vital role in both physical and mental health, and choosing the right melatonin supplement can make a real difference. With our recommendations based on brand reputation, purity, formulation, and absorption, you now have a solid foundation to make the best decision for your sleep needs.