
How Long Does Curcumin Take To Work?
How long does curcumin take to work? The answer isn’t the same for everyone. Some people start noticing health improvements within just 1–3 weeks of use, while others may need 4–8 weeks to feel a clear difference*.
So, what causes this variation? The truth is, there’s no “one-size-fits-all” timeline—each body responds to curcumin differently. Curious to know why? Let’s dive into the details in the article below.
Before exploring further, please read the disclaimer located at the end of this webpage.
Key Takeaways
- Curcumin extract is found in turmeric, which is the most concentrated and nutritious part.
- On average, curcumin's effectiveness is clearly shown after 4 - 8 weeks, persistently using as directed by your doctor/nutritionist.
- The time to show the effectiveness of curcumin is related to many factors such as dosage, duration of use,...
How Long Does Curcumin Take to Work?
Curcumin extract from turmeric is not a miracle drug, it can show effects immediately after use but takes up to 4 - 8 weeks. However, this is only for reference because each person's absorption and metabolism ability is different, which will affect the time to show effects [4].
Besides, the time for curcumin to show positive results for health is also related to many factors such as the way of supplementation (capsule/tablet, powder,...), diet and lifestyle, health status, purpose of use,...
For example, Erzsi Szabo shared on Quora that she used curcumin combined with cherry and black pepper to relieve joint discomfort and found that the problem subsided after 3 weeks.*
Or in the topic How long does it take for turmeric to work for weight loss?, many people noticed a good appetite and less bloating after using curcumin extract for 2-4 weeks, and when combined with a reasonable diet and exercise, after 8 weeks, the weight loss effect was very clear.*
Read more: What Foods Have Curcumin? Ways to Supply Curcumin
Factor That Affects on Curcumin Active Duration

Let's learn more about the factors that affect the time curcumin takes to be effective for users:
Dosage and Timing
The higher the dosage, the faster the effect, but the more important is the suitability. Those looking to use curcumin extract to support the body’s natural anti-inflammatory response, maintain microbial balance, and promote joint comfort often need 500 - 1,000 mg/day, continuously for at least 2 - 4 weeks to get results.
Those who want to maintain a good weight, improve digestion may need to use 1,000 - 1,500 mg/day, continuously for 4 - 8 weeks to achieve the expected effect [1,2].
Along with that, the time of day of curcumin use also affects the effectiveness of curcumin extract. Because this extract contains nutrients that are soluble in oil, taking it after meals will help the body absorb it better than taking it on an empty stomach (before meals).
In addition, taking the recommended amount all at once is often not as good as dividing it into 2 times a day, allowing the body to metabolize it effectively, such as 500 mg/time in the morning and afternoon [1,2].
Bioavailability Concerns
Curcumin is not a compound that dissolves well in water, but dissolves in oil. Moreover, this nutrient is metabolized very quickly in the body, so it is difficult to retain for a long time, but is quickly eliminated when it reaches the liver - becoming an "immobile" form.
Because curcumin is not easily absorbed through the digestive tract due to its low solubility in water and poor permeability into the intestine.
Along with that, you may not know that curcumin is not stable at alkaline pH, further affecting its bioavailability. Therefore, to fully absorb curcumin, it is necessary to combine many different factors.
Including creating an oily environment, maintaining a stable pH instead of alkaline (<7.0 pH) and especially maintaining daily, regular use so that the curcumin concentration reaches a level that can create good effects on health (Agrawal & Jaiswal, 2022).
Forms

Curcumin exists in two forms, keto and enol, in which keto is the stable form and has strong antioxidant properties. And there are currently many pharmaceutical formulas containing keto - curcumin such as capsules, tablets, powders, liquid extracts or tinctures, etc. Each type has different advantages and disadvantages, but capsules/tablets are the choice that many users love.
The reason is that capsules/tablets have a carefully measured turmeric content, suitable for the needs, not too much or too little. At the same time, the way to use it is very simple, just take the capsule/tablet with warm water, after meals. And moreover, it is easy to carry out to use when needed without taking up too much space in your bag [6].
Curcumin Immediate vs. Long-Term
Curcumin can have immediate or long-term effects depending on how it is used. Typically, curcumin shows rapid pain relief when using high doses of curcumin similar to NSAIDs but only lasts for a few hours.
But if you want to improve resistance, support long-term pain relief, improve cognition, reduce cholesterol, ... then of course curcumin cannot meet the needs and must be used persistently for many months. Or athletes need to recover their physical strength and must use curcumin at a maintenance dose for several consecutive months (Hewlings & Kalman, 2017).
How to Recognize the Effects of Curcumin
Curcumin is a powerful anti-inflammatory and antibacterial active ingredient found in turmeric. With many outstanding uses such as supporting joint comfort, flexibility, and overall joint function., beautifying the skin, stabilizing weight, regulating cholesterol in the body, etc., curcumin extract is being used more and more.
You can clearly see some signs that curcumin has taken effect after use such as gradually reducing inflammation symptoms, a healthy body, fresh skin, etc. However, this is the result of a long process of persistent use, not just a day or two.
Besides, you also need to pay attention that curcumin can cause side effects if overdosed. Typically, you find yourself having digestive disorders, stomach pain, fatigue, dizziness, ... Therefore, you should consult your doctor/nutritionist carefully before using it to ensure safety.
How Long Does Turmeric Stay in Your System?

The active compounds in curcumin extracts are usually lost after 24 hours because the half-life of that nutrient is 6 - 7 hours and is excreted through the urine.
However, a small amount of curcumin can remain in the body longer, in the liver and fat tissue. The reason for this is that turmeric is a food that contains substances that are soluble in fat, so wherever there is fat, there is curcumin [3].
Which Forms of Curcumin Should You Use?
Currently, on the market, there are many ways to supplement curcumin extract, and each type has its own advantages and limitations. Among them:
- Turmeric powder: This is a familiar form of curcumin extract for many users, often used in cooking, but according to Healthline, this type of extract is quite low, only 2 - 8%. Therefore, the effectiveness of curcumin shows that it takes a long time, or is unclear.
- Curcumin from the concentrated form of curcuminoid: This is the type of extract that contains the most curcumin, up to 80 - 95%. With such strong properties, you can clearly get the expected effect.
- Combining curcumin with piperine: Thanks to piperine in black pepper, the ability to absorb curcumin is significantly improved and stays in the body longer. Therefore, users will see the positive effects of curcumin extract after only a short time.
- Combining phospholipid with curcumin: This is the perfect duo to help curcumin dissolve quickly and be absorbed well by the body. Typically, the phospholipids selected come from sunflower seed oil extract.
- Nanoparticles (Theracurmin): This form of curcumin extract helps the body absorb faster than regular extracts. Thanks to that, the body can also easily metabolize and absorb it.
- Liposome curcumin: Liposomes are likened to small lipid bubbles, creating a great fat environment for curcumin to dissolve quickly and absorb effectively.
In general, each form of curcumin has its own advantages and limitations. Below is a detailed summary table for your reference:
Form |
Absorption |
Pros |
Cons |
Best Use |
Curcumin Extract (95%) |
Low |
Potent, affordable |
Needs piperine, low bioavailability |
Budget-friendly supplementation |
Curcumin + Piperine |
High (12,000%) |
Effective, affordable |
Piperine may interfere with drugs |
General health, weight loss |
Phytosome (Meriva®) |
Very high (20–30x) |
Easy on stomach, well-researched |
More expensive |
Inflammation, joint health |
Liposomal Curcumin |
Very high |
High absorption, gut-friendly |
Expensive, soy allergy risk |
Systemic inflammation |
Nanocurcumin |
Extremely high |
Advanced therapeutic absorption |
Very expensive, limited commercial availability |
Clinical or experimental use |
Turmeric Powder |
Very low |
Natural, safe, widely used in cooking |
Ineffective for therapy unless highly dosed |
Daily food or low-intensity health support |
The important thing is not to choose the most modern type, but to choose the best curcumin supplements that suits the user's body. For detailed information, you should contact your doctor for detailed advice.
Is it Safe to Take Turmeric Daily?
Depending on how you supplement curcumin extract, the answer is YES or NO. In particular, if you only enjoy the nutrients from curcumin extract through fresh curcumin extract, when cooking, you can absolutely use it every day. But the dosage should not exceed 2 grams/day (about 2 teaspoons).
In case you are using functional foods to supplement curcumin extract, as mentioned above, you can use 500 - 1,500 mg/day, divided into 2 times/day according to the manufacturer's instructions.
Those who have to use more than 1,500 mg of curcumin extract/day for medical treatment purposes must have a doctor's prescription to ensure safety.

In addition, note that some subjects are not suitable for daily use of curcumin extract such as people with gallstones or bile duct obstruction, those who are using blood thinners or diabetes medications, pregnant and lactating women, etc.
Conclusion
The above article has answered the question of how long it takes for curcumin to be effective as expected. Hopefully, through this, you will find the type of curcumin extract that is right for you. But to increase the effectiveness, what you cannot ignore is combining it with a healthy diet, lifestyle and regular health check-ups to have a healthy body!
Testimonial Disclaimer
*The testimonials presented on this website are provided by individuals based on their personal experiences with our products. These testimonials represent individual opinions and experiences, which may not be typical or applicable to all users of our products. Results may vary depending on a variety of factors, including individual health, lifestyle, and adherence to product usage instructions.References
- [1] Akbari, M., et al. (2019). The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Frontiers in Pharmacology, 10. https://doi.org/10.3389/fphar.2019.00649.
- [2] Noorbakhsh Alivand, et al. (2024). The Effects of Curcumin Supplementation on Body Weight, Body Mass Index, and Waist Circumference in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. MedRxiv. https://doi.org/10.1101/2024.10.08.24315114.
- [3] Vareed, S. K., et al. (2008). Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects. Cancer Epidemiology Biomarkers & Prevention, 17(6), 1411–1417. https://doi.org/10.1158/1055-9965.epi-07-2693.
- [4] Tang, M., et al. (2008). Effect of cinnamon and turmeric on urinary oxalate excretion, plasma lipids, and plasma glucose in healthy subjects. American Journal of Clinical Nutrition, 87(5), 1262–1267. https://doi.org/10.1093/ajcn/87.5.1262.
- [5] Agrawal, N., & Jaiswal, M. (2022). Bioavailability enhancement of curcumin via esterification processes: A review. European Journal of Medicinal Chemistry Reports, 6, 100081. https://doi.org/10.1016/j.ejmcr.2022.100081.
- [6] Turmeric Information | Mount Sinai - New York. (2016). Retrieved May 22, 2025, from Mount Sinai Health System website: https://www.mountsinai.org/health-library/herb/turmeric.
- [7] Hewlings, S., & Kalman, D. (2017). Curcumin: A Review of Its Effects on Human Health. Foods, 6(10), 92. https://doi.org/10.3390/foods6100092.
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