How To Use Goldenseal Root? Dosage And Timing

How To Use Goldenseal Root? Dosage And Timing

Goldenseal, a medicinal plant mainly found in North America, is famous for its medicinal properties. Its active ingredients are hydrazine and Berberine, which have antiseptic properties. Goldenseal is available in liquid, tablet, and capsule forms standardized to active ingredients. How to use goldenseal root effectively is a question that receives much attention. This article aims to provide valuable insights into this remarkable plant's appropriate dosage, timing and uses.


How to Use Goldenseal Root In the Traditional Uses

Goldenseal is a common natural remedy for upper respiratory tract infections

Goldenseal is a common natural remedy for upper respiratory tract infections, including the common cold.

Its antibacterial activity in vitro is believed to be due to its alkaloids, with Berberine being the most common. [1]

Studies on cell cultures in the laboratory and animals have shown that Berberine can help combat infections caused by bacteria and viruses, including common cold-causing viruses. [2]

Native Americans used Goldenseal to relieve irritations and inflammation in the respiratory, digestive, and urinary mucous membranes.

They often applied it topically for skin and eye infections and historically used it as a mouthwash to help heal canker sores.

Goldenseal is often combined with echinacea for colds and flu, primarily to ease sore throat discomfort. Early 20th-century Eclectic physicians valued Goldenseal as a remedy for stomach and intestinal problems.

How Do You Take Goldenseal Root?

Recommended Dosage for Goldenseal Root

Supplements from dried Goldenseal roots are typically used at doses ranging from 0.5 to 10 grams per dose per day

Supplements from dried roots are typically used at doses ranging from 0.5 to 10 grams per dose per day, while alcohol tinctures and liquid extracts are commonly administered at doses of 0.3 to 10 mL three times a day. [3]

Goldenseal can also be consumed as a tea by steeping 2 teaspoons of dried herb in 1 cup (240 mL) of hot water for about 15 minutes.

The recommended dosage when using Goldenseal is 1 gram of pure Goldenseal powder extracted from the root.

Mix a quarter (¼) teaspoon of Goldenseal Powder (1 gram = 1000mg) into 8-10 oz of water to use. You can use it with juice or smoothies to increase it even more.

You can also take an empty capsule without water.

Goldenseal benefits include strengthening the immune system, promoting healthy sinuses, and supporting digestive health.

Ways to Take Goldenseal Root

You can use Goldenseal powder as a tea or tincture that can soothe a sore throat

How to Use Goldenseal Root Powder: You can use Goldenseal powder as a tea or tincture that can soothe a sore throat. It can be mixed with water or juice and taken orally. You can 'smell' up each nostril, and it will support the sinus areas.

How to Take Goldenseal Drops: Goldenseal is also used topically as a lotion, eye wash, ear drop, and vaginal douche and administered by placing drops under the tongue or mixing with water or juice.

How to Take Goldenseal Tincture: Typically taken by adding a few drops to water or juice and consumed orally.

Combine Goldenseal Root and Other Herbs: Goldenseal root is commonly blended with other herbs in herbal mixtures or teas to create synergistic effects. It is often combined with echinacea in different over-the-counter herbal remedies for colds and flu. Echinacea, native to North America, is widely utilized for treating infections, such as the common cold. [4], [5]

Other Forms of Goldenseal Root to Take: Capsules and tablets are also available for convenient oral consumption.

This video will provide you with comprehensive guide about the benefits of Goldenseal root and how to use Goldenseal root capsules effectively:

How to Take Goldenseal Root for Specific Condition

How to Use Goldenseal for Ear Infection: Goldenseal is used for ear problems like ringing, earaches, and deafness. It contains Berberine, which fights bacteria and fungi.

Based on early research, Berberine may also lower blood pressure, improve irregular heartbeats, reduce blood sugar, and lower "bad" LDL cholesterol levels. [3]

Goldenseal root extract can be diluted and applied topically to the affected ear for ear infections. Alternatively, it can be taken orally to support the immune system's response to infection.

How to Use Goldenseal Powder for Tinnitus: Goldenseal powder, when taken orally, may help ease tinnitus symptoms, but there is limited research on its effectiveness for this condition.

How to Use Goldenseal for Sinus Infection: Goldenseal root may help alleviate symptoms of sinus infections when taken orally or as a nasal rinse.

How to Use Goldenseal for Eyes: Goldenseal root is not commonly used for eye-related conditions, and caution should be exercised when using any herbal remedy near the eyes.

How to Use Goldenseal for UTI: Goldenseal root may help support urinary tract health and alleviate symptoms of urinary tract infections when taken orally.

Best Way to Take Goldenseal

How To Take Goldenseal Root For Specific Condition

There aren't any studies that suggest what dosages of Goldenseal are the most beneficial. Goldenseal supplements come in many forms so that dosages can vary.

Taking Goldenseal in capsule or powder form is supposed to be optimal. It can also be applied topically to the skin as an ointment, balm, or cream for rashes, itching, wounds, acne, eczema, and ulcers.


Can You Take Goldenseal Daily?

While Goldenseal can be taken daily for short periods, it's not recommended for long-term use due to potential side effects and the risk of developing antibiotic resistance. Goldenseal may lead to side effects like nausea, vomiting, and impaired liver function. [6]

Can You Take Goldenseal While Pregnant?

Limited research suggests potential risks of using Goldenseal during pregnancy and breastfeeding. Animal studies indicate that Berberine, a key compound in Goldenseal, may lead to lower weight in mothers and babies, increase the risk of preterm birth due to uterine contractions, and worsen jaundice in newborns, possibly causing brain damage. [7]

What Not to Take with Goldenseal?

Goldenseal, especially its main component berberine, may interact with various medications, affecting their effectiveness or increasing the risk of side effects. It's crucial to consult a doctor before using Goldenseal if you're taking any prescription or over-the-counter drugs. Specific interactions include elevated levels of cyclosporine, increased blood levels of digoxin, potential reduction in the effectiveness of tetracycline antibiotics, and heightened risk of bleeding when used with blood thinners like Warfarin, Plavix, and Aspirin.


Goldenseal root has been used for centuries as a traditional medicine for various conditions. It is known for its many health benefits, including its ability to strengthen the immune system, support digestive health, and reduce sinus infections. This article has helped you learn how to use goldenseal root most effectively.


[1] Ettefagh, K. A., Burns, J. T., Junio, H. A., Kaatz, G. W., & Cech, N. B. (2010). Goldenseal (Hydrastis canadensisL.) Extracts Synergistically Enhance the Antibacterial Activity of Berberine via Efflux Pump Inhibition. Planta Medica, 77(08), 835–840.
[2] Chu, M., Ding, R., Chu, Z., Zhang, M., Liu, X., Xie, S., Zhai, Y., & Wang, Y. (2014). Role of berberine in anti-bacterial as a high-affinity LPS antagonist binding to TLR4/MD-2 receptor. BMC Complementary and Alternative Medicine, 14(1).
[3] Working, I. (2016). Exposure Data.; International Agency for Research on Cancer.
[5] Catanzaro, M., Corsini, E., Rosini, M., Racchi, M., & Lanni, C. (2018). Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea. Molecules, 23(11), 2778–2778.
[6] Goldenseal-Drug Interactions: A Concern? (2021, July 7).
[7] Rad, K., Rameshrad, M., & Hosseinzadeh, H. (2017). Toxicology effects of Berberis vulgaris (barberry) and its active constituent, berberine: a review. DOAJ (DOAJ: Directory of Open Access Journals), 20(5), 516–529.
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Ralph S. Albert, with over 10 years of expertise in nutrition and research, now heads the Research division at Vinatura Supplements. His dedication and extensive knowledge ensure top-quality articles on nutrition and health, collaborating with a skilled team. He has successfully completed The VINATURA Expertise Research Training Program, underscoring his commitment to Vinatura's mission. Ralph has also published numerous articles and conducted valuable research in the field, making him a trusted resource for individuals on their wellness journey.

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