Saw Palmetto For PCOS: Does It Help And How To Use It?

Saw Palmetto is commonly known as a trusted companion for men in supporting prostate health. However, surprisingly, this herb is also gaining attention among women—particularly those dealing with polycystic ovary syndrome (PCOS).

So what makes a plant traditionally associated with male health beneficial for a female hormonal disorder? Let’s explore the mechanisms and benefits of Saw Palmetto for PCOS in this article.

Saw Palmetto Background

Saw Palmetto, native to the southeastern United States, has been used for thousands of years to support urinary and reproductive health.

In modern medicine, it is widely known for relieving symptoms of benign prostatic hyperplasia (BPH), enhancing prostate health, and supporting reproductive function. It is also promoted for stimulating hair growth and boosting vitality [1].

Scientifically, in vitro and animal studies have identified the following key mechanisms of action [1]:

• Acts as an anti-androgen in multiple sites.
• Inhibits 5α-reductase, which converts testosterone to DHT—a hormone linked to BPH and hair loss.
• Blocks androgen receptors, limiting hormone binding in prostate cells. 
• Inhibits estrogen receptors in the prostate, helping balance hormones and reduce tissue proliferation.
• Does not affect PSA levels, indicating it may be safe for use during prostate cancer monitoring.

Some studies also show that saw palmetto extract (SPE) can alleviate urinary symptoms by inhibiting the increased expression of α1-adrenoceptors in the prostate triggered by testosterone.

This suggests SPE may act directly on related receptors, supporting improvement in urinary issues caused by BPH or overactive bladder [2].

Saw Palmetto is currently available in many forms, including capsules and tablets, and is often combined with other herbs.

Over 100 commercial products are on the market. Notably, its side effects are usually mild and rare, with minimal drug interactions, making it a popular and safe option for men dealing with prostate issues or hair loss [1].

A study in Trinidad and Tobago found that herbal product usage—especially Saw Palmetto—is common among men with prostate problems. Based on responses from 200 participants [3]:

• 42.5% used herbal remedies, with 62.3% of them choosing Saw Palmetto.
• 25% believed it may help reduce prostate cancer risk.
• 36% thought it was effective in relieving BPH symptoms.

Recently, Saw Palmetto has drawn attention for its potential in supporting women with PCOS. Is this claim true? Let’s find out below.

Does Saw Palmetto Help with PCOS?

Saw palmetto has been studied primarily for its potential to support hormonal balance, particularly by helping to reduce excess androgens like testosterone [4].

Some individuals with polycystic ovary syndrome (PCOS) have explored saw palmetto as a natural option to support skin health and manage symptoms such as acne and unwanted facial hair.

For example, a user of the Pureafina supplement containing saw palmetto reported improvements in acne around the upper lip and chin, as well as a reduction in facial hair. These observations were particularly noted in relation to managing symptoms associated with elevated androgen levels.*

However, it is important to note that research on saw palmetto specifically for PCOS is still limited. Most available information focuses on its potential benefits for specific symptoms, such as acne, excess facial hair, and hormone balance, rather than its effectiveness for PCOS as a whole.

Therefore, while saw palmetto may show promise in certain areas, it is not an established or widely recognized treatment for PCOS.

As with any supplement, individuals interested in using saw palmetto for hormonal support should consult with a healthcare professional to ensure it is appropriate for their personal health needs [4].

Related article: 5 Best Saw Palmetto Supplements for Hormone Balance

How Does Saw Palmetto Benefit PCOS?

Saw Palmetto is considered a plant-based anti-androgen and is commonly used for hormone-related conditions such as PCOS, hirsutism, acne, and BPH [5].

Its supportive mechanisms for PCOS include [4]:

• Reducing excess testosterone: PCOS often comes with elevated androgens, especially testosterone. Saw Palmetto inhibits 5-alpha-reductase—the enzyme that converts testosterone into the more potent DHT, which is linked to acne, hair loss, and menstrual irregularities.
• Improving symptoms: Saw Palmetto use may reduce acne, scalp hair loss, excessive hair growth (hirsutism), and help regulate menstrual cycles.
• Stabilizing the HPA axis: As an adaptogenic herb, it helps modulate the body’s stress response, thereby supporting hormonal balance, which is often disrupted in PCOS.

"Studies have shown that it possesses androgenic properties that can decrease androgen activity. These properties include reducing testosterone levels, enhancing balance, and promoting frequent ovulation, all of which enhance the chances of conception." "The antioxidant attributes of saw palmetto may enhance well-being by diminishing inflammation and symptoms associated with PCOS." – Excerpt from "From Nature to Nurture: A Review of Herbal Approaches to Polycystic Ovary Syndrome (PCOS)" by Kshama & Ray, 2024 [6]

This highlights how Saw Palmetto may reduce androgens, support ovulation, and improve fertility in women with PCOS. Additionally, its anti-inflammatory and antioxidant properties can ease related symptoms.

According to Nourished Natural Health, Saw Palmetto supports PCOS treatment by reducing androgens (like DHT), which are responsible for acne, hair loss, and hirsutism. It also aids in regulating menstrual cycles and enhancing reproductive health. However, they emphasize that it should be used as part of a holistic care strategy, not as a complete replacement for medical treatment.*

What PCOS Symptoms Can Saw Palmetto Support?

PCOS is a common hormonal disorder among women of reproductive age. A study (Kumar et al., 2022) on rats revealed that PCOS is caused by an imbalance in steroid hormones (increased androgens, reduced estrogen) and impaired aromatase enzyme activity, leading to anovulation and ovarian cyst formation [7].

PCOS can result in:

• Weight gain, especially abdominal fat due to excess "bad" estrogen.
• High blood sugar due to insulin resistance.
• Elevated blood lipids: Increased TC, TG, LDL – decreased HDL.
• Heart rate variability and irregular rhythm (HR, LF/HF).
• Reduced antioxidant activity (decreased CAT, SOD, GSH).
• Enlarged ovaries with many underdeveloped follicles and no ovulation.

Core symptoms include:

• Irregular menstruation (oligomenorrhoea)
• Anovulation (absence of ovulation) → leading to infertility
• Hyperandrogenism (high male hormones) → excess facial/body hair, acne
• Obesity and bilateral enlarged ovaries

These symptoms can significantly impact mental and physical health.

Studies using Saw Palmetto in rats showed the following benefits:

• Weight reduction: Helps convert harmful estrogens into inactive forms for elimination [7].
• Lower androgen levels: Inhibits 5α-reductase – the enzyme that converts testosterone into DHT, a more potent androgen linked to acne, hair loss, and hirsutism [6], [7].
• Reduces hair loss and promotes hair growth: Due to its anti-androgenic properties, saw palmetto is widely used to support hair health [8].

• Hormonal balance: Improves FSH secretion, supporting follicle development and ovulation [7].
• Improves blood sugar control: By reducing insulin resistance, it supports menstrual regularity and ovulation [7].
• Improves lipid profile: Reduces total cholesterol (TC), triglycerides (TG), and LDL, while increasing HDL – benefiting cardiovascular health [7].
• Supports autonomic nervous system balance: Helps regulate heart rate and LF/HF values [7].
• Anti-inflammatory and antioxidant effects: Increases antioxidant enzyme activity (CAT, SOD, GSH). These effects help ease inflammation – a factor that worsens PCOS – and improve overall health [6], [7].
• Restores ovarian structure: Fewer abnormal follicles, more mature follicles, and presence of corpus luteum (a sign of ovulation) [7].
• Improves ovulation: By lowering androgen and prolactin levels, saw palmetto helps restore the ovulation cycle and regulate menstruation [6].
• Supports fertility: Through enhanced ovulation and hormonal balance, saw palmetto may increase the chances of conception in women with PCOS [6].

Saw Palmetto shows promising potential in supporting PCOS treatment thanks to its comprehensive effects on hormones, metabolism, and ovarian function. However, further clinical studies in humans are needed to confirm its effectiveness.

How Much Saw Palmetto Should a Woman Take for PCOS?

The recommended dosage of Saw Palmetto is 160–450 mg, twice daily [9].

Choose a standardized extract containing 45–95% fatty acids, as these are the main bioactive compounds [9].

This dosage has been safely used in men and is also applied by herbal medicine experts for women, especially in cases of hormonal imbalance.

Important notes when using Saw Palmetto for PCOS:

• Avoid use during pregnancy or breastfeeding, as safety data is lacking.
• Saw Palmetto may reduce the conversion of testosterone to DHT, helping with excess hair growth and male-pattern hair loss.
• Use consistently for at least 8–12 weeks to evaluate effectiveness [9], as individual responses may vary – be patient and give your body time to respond.

Other Benefits of Saw Palmetto for Women’s Health

Beyond its role in hormone regulation and improving PCOS symptoms, Saw Palmetto offers a range of other health benefits for women:

Menstrual and Menopausal Health

• Reduces inflammation and supports a more regular menstrual cycle.
• May help relieve perimenopausal and menopausal symptoms such as vaginal dryness, hot flashes, hair loss, and mood changes.

Skin and Hair

• Improves female-pattern hair loss (androgenetic alopecia): Helps reduce hair loss caused by hormonal imbalances, often seen in menopausal women or those with PCOS.
• May stimulate hair growth with consistent use, either orally or topically (as a serum or herbal shampoo).
• Enhances skin health through its anti-inflammatory and antioxidant properties, helping to soothe the skin and reduce acne.
• Supports sebum balance and unclogs pores – especially helpful for skin affected by DHT hormones.

Urinary Health

• Supports bladder control, particularly reducing frequent urination during the day (noted after 12 weeks of use).

Possible Side Effects:

Some individuals may experience mild side effects such as headaches, nausea, diarrhea, dizziness, or reduced blood clotting ability.

Do NOT use Saw Palmetto if you are:

• Pregnant or breastfeeding.
• Using birth control pills (as it may reduce their effectiveness).
• Have a history of hormone-sensitive cancers.
• Taking blood thinners (e.g., warfarin, clopidogrel).
  

Recommendations:

• Always consult a healthcare professional before use, especially if you have underlying health conditions or are taking medications.
• Choose high-quality products from reputable manufacturers.

Other Supplements for PCOS

While medications like metformin and thiazolidinediones have been standard treatments, they come with side effects and may not be effective for patients who are not overweight or insulin-resistant.

Several natural compounds are being studied and have shown promising results in supporting PCOS treatment, including [11]:

• Curcumin (from turmeric): Helps reduce inflammation, lower LH hormone levels, decrease insulin resistance, and support ovulation.
• Vitamin D: Improves insulin sensitivity, reduces inflammation, and helps regulate menstrual cycles.
• Inositol: Aids blood sugar regulation, improves egg quality, and restores natural ovulation.
• CoQ10: Anti-inflammatory, boosts cellular energy, and supports ovarian function.

These nutrients offer a safe and effective approach to improving PCOS, especially for those who do not respond well to conventional medications. However, further research is needed, and medical consultation is advised before starting any new supplement.

Conclusion

Saw Palmetto is a promising herbal remedy for supporting PCOS treatment, especially in reducing androgen levels and balancing hormones. However, its use should be monitored and guided by healthcare professionals to ensure both effectiveness and safety.