Why Should You Take Nattokinase On An Empty Stomach?

To maximize its effectiveness, Nattokinase should be taken on an empty stomach. This timing helps the enzyme avoid interaction with food proteins, allowing it to enter the bloodstream intact and support systemic functions. The following article will help you better understand the best time to take Nattokinase.

Why Should You Take Nattokinase On an Empty Stomach?

Taking Nattokinase on an empty stomach helps maximize its effectiveness. Nattokinase, a natural enzyme from the Japanese dish Natto, helps break down blood clots and other unwanted protein build-ups.

If taken with food, it may bind with dietary proteins and act more like a digestive enzyme.Studies suggest that enzymes work better when taken without food, as they can act directly in the body instead of focusing on digestion [3].

That’s why taking Nattokinase on an empty stomach helps it reach your bloodstream and do its job effectively [1].

Is Nattokinase Absorbed In The Stomach?

Contrary to popular belief, Nattokinase is not destroyed by stomach acid. While many assume that this enzyme breaks down in the highly acidic environment of the stomach (pH ~1), research suggests otherwise.

A study by Machaon Diagnostics in the U.S. demonstrated that Nattokinase is acid-resistant and can survive digestion. Cardiovascular specialists confirmed that the enzyme remains intact as it enters the bloodstream, allowing it to deliver its intended systemic benefits effectively [2].

How to Take Nattokinase for Best Results?

Best time to take:  Take it 30 minutes before a meal or 1 hour after eating. This helps the enzyme reach your bloodstream without being used up digesting food.

With or without food? Although Nattokinase can be taken with foods like rice, eggs, or butter, doing so may lessen its effectiveness. When consumed with meals, it may act more as a digestive enzyme instead of delivering full-body support.

One Amazon user, Ang, aged 53, reported positive effects after using a supplement containing Nattokinase, noting noticeable improvements in his well-being.*

Can it be combined with other supplements?

Yes, Nattokinase can be safely combined with other supplements. It pairs particularly well with enzymes like Serrapeptase and Lumbrokinase, offering synergistic benefits such as supporting cardiovascular health, enhancing circulation, strengthening immune function, and providing antioxidant support.

While Nattokinase offers promising benefits, it’s important to prioritize your safety. Always consult a healthcare professional before adding it to your routine—especially if you’re on medications or have existing health conditions.

This ensures proper dosage and helps tailor the combination of Nattokinase with other supplements to best support your overall well-being.

Learn more: How Much Nattokinase Per Day Should You Take?

Should You Eat Natto Instead?

Nattokinase supplements are a convenient alternative to traditional Natto, especially for those who find its strong smell, sticky texture, or taste off-putting.

While Natto—a fermented soybean dish from Japan—is naturally rich in Nattokinase and packed with protein, vitamins, and beneficial bacteria, it’s not always easy to find or consume regularly.
Supplements provide a standardized dose without the sensory challenges, making them a more accessible and consistent option for many people.

Precautions When Using Nattokinase

Avoid nattokinase if you have a severe allergy to it or any components (part or ingredient) that make up its Nattokinase supplement. You'll also want to avoid Natto if you have a soybean allergy.

Pregnant or breastfeeding women, children, and adults over 65 should use Nattokinase with caution as there's limited information regarding its long-term safety for these groups.

Individuals with blood disorders should only use Nattokinase with medical guidance.

Conclusion

The numerous health benefits of Nattokinase make it an invaluable asset in the realm of nutritional supplements. Strategic consumption notably enhances its effectiveness. For optimal absorption and utilization, it is advisable to take Nattokinase on an empty stomach.

This ensures maximum efficacy and promotes a variety of health-supporting effects. However, individual responses may vary, and it is essential to consult a healthcare professional for personalized advice. As ongoing research uncovers the potential of this enzyme, it becomes clear that Nattokinase offers promising opportunities for personal health optimization.