Dr. John A. Rathmacher is a distinguished researcher and Director of Clinical Research at MTI BioTech Inc. With a robust background in metabolic technologies and exercise physiology, Dr. Rathmacher has made significant contributions to the understanding of muscle physiology and nutrition, particularly through his work on β-hydroxy-β-methylbutyrate (HMB) and its effects on muscle metabolism.

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Dr. John A. Rathmacher is a distinguished researcher and Director of Clinical Research at MTI BioTech Inc. With a robust background in metabolic technologies and exercise physiology, Dr. Rathmacher has made significant contributions to the understanding of muscle physiology and nutrition, particularly through his work on β-hydroxy-β-methylbutyrate (HMB) and its effects on muscle metabolism.

Professional Journey

Dr. John A. Rathmacher's career is marked by a series of prestigious roles and positions:

  • Director of Clinical Research at MTI BioTech Inc., where he leads clinical research initiatives focusing on metabolic technologies.
  • Senior Researcher at Metabolic Technologies Inc. from July 1996 to December 2019, contributing extensively to research in muscle metabolism and nutritional supplements.
  • Postdoctoral Researcher at Iowa State University’s Department of Animal Science from December 1993 to September 1996, where he honed his expertise in exercise physiology and metabolism.

Research and Innovation

Dr. Rathmacher’s research has significantly advanced the field of muscle physiology and nutritional supplementation. Notable contributions include:

  • Effect of leucine metabolite β-hydroxy-β-methylbutyrate on muscle metabolism during resistance-exercise training published in the Journal of Applied Physiology (1996), which provided early insights into HMB’s impact on muscle metabolism.
  • Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism in The Journal of Physiology (2013), demonstrating the effects of HMB on muscle protein metabolism.
  • Nutritional Treatment for Acquired Immunodeficiency Virus‐Associated Wasting Using β‐Hydroxy β‐Methylbutyrate, Glutamine, and Arginine in Journal of Parenteral and Enteral Nutrition (2000), highlighting HMB’s role in managing muscle wasting conditions.
  • Nutritional supplementation of the leucine metabolite β-hydroxy-β-methylbutyrate (HMB) during resistance training in Nutrition (2000), showing its benefits in resistance training.

Awards and Recognition

Dr. Rathmacher has been recognized for his groundbreaking work in exercise science and muscle physiology, including several citations and influential publications in top journals.

Professional Affiliations and Leadership Roles

  • Director of Clinical Research at MTI BioTech Inc., overseeing critical research on metabolic technologies.
  • Former Senior Researcher at Metabolic Technologies Inc., contributing to key advancements in muscle metabolism research.
  • Postdoctoral Researcher at Iowa State University, where he began his extensive research career in exercise physiology.

Dr. John A. Rathmacher’s contributions have profoundly impacted the fields of nutrition, exercise science, and muscle physiology. His research continues to shape understanding and practices in metabolic technologies and performance enhancement.

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