Yohimbine Vs. Horny Goat Weed: Which One Should You Choose For ED?

Both Horny Goat Weed and Yohimbe have specific benefits in supporting erectile dysfunction. However, Horny Goat Weed is used for ED and herbal supplementation (mainly kidney tonic). Yohimbe, on the other hand, is prescribed for ED and sexual dysfunction caused by SSRIs (antidepressants). So, which one should you choose for your erectile dysfunction issue? Let's find out in this article.

Yohimbine Vs. Horny Goat Weed: Which One Should You Choose For ED?

While both Yohimbine and Horny Goat Weed are used in supporting erectile dysfunction, not everyone is suited to both herbal options.

Some prefer Horny Goat Weed because it is a natural herb with fewer side effects. In contrast, others opt for Yohimbine because of its quicker effects.

Yohimbine's notable function is supporting ED and sexual dysfunction caused by SSRIs, while Horny Goat Weed supports managing ED and herbal supplementation.

Another consideration is that Yohimbine has more clinical evidence supporting its effectiveness and safety in supporting ED compared to Horny Goat Weed, which lacks clinical solid evidence.

However, this article will help you understand the pros and cons of each herb so that you can make an informed choice. Let's delve into the specifics of each type in the following sections.

Read more: Tribulus Vs. Horny Goat Weed: Which is Better & How to Combine?

What Is Yohimbine?

Yohimbine is an alkaloid found in the bark of the Pausinystalia yohimbe tree. It has been studied as a potential method for Erectile Dysfunction (ED) [1].

How Does Yohimbine Work?

Animal studies suggest that Yohimbine can improve sexual function by enhancing penile erection and sexual desire.

The exact mechanism of action of Yohimbine is not fully understood but may be related to [1]:

• Blocking alpha-2 receptors, Yohimbine helps widen blood vessels, increasing blood flow to various body parts, especially the genital organs.
• It also enhances arousal and releases norepinephrine, a neurotransmitter that plays a crucial role in regulating sexual desire.
• Stimulating the release of nitric oxide (NO) from nerve endings promotes smooth muscle relaxation in the penis.

What Are the Benefits of Yohimbine for Health?

Animal studies suggest that using Yohimbine can enhance sexual performance. Additionally, it may reduce ejaculation latency, increase erection frequency, and improve sexual arousal [1].

Moreover, research indicates that combining Yohimbine with NO-releasing enhancers can improve the effectiveness of supporting ED, a combination worth considering [1].

Furthermore, Yohimbine may be beneficial in supporting sexual dysfunction caused by medications in patients with depression. This includes those affected by serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants. Yohimbine can also help address issues such as reduced pleasure sensation and ejaculation disorders caused by these medications.

To date, Yohimbine has been used to support several other conditions, including:

• Drug-induced erectile dysfunction: Studies have combined Yohimbine with other medications like isoxsuprine and pentoxifylline to support erectile dysfunction in patients with arterial insufficiency and venous leakage. Results showed a reasonably positive response rate, although incomplete, and few side effects.
• Obesity
• Alcohol addiction
• High blood pressure
• Orthostatic hypotension
• Parkinson's disease
• Alzheimer's disease
• Depression
• Generalized anxiety disorder
• Panic disorder
• PTSD
• Patients with sleep disorders
• Peripheral neuropathy

Read more: Horny Goat Weed Vs Ginseng: Which One Should You Choose?

Side Effects of Yohimbe

There have been reports of patients experiencing temporary symptoms of increased blood pressure, elevated heart rate, and others after overdosing on 200 mg, 250 mg, and 350 mg of Yohimbine. However, all symptoms diminished and disappeared within 1-2 days after discontinuing the herb [1].

Another case report involved a 16-year-old female who took approximately 250 mg of Yohimbine in the evening and subsequently experienced severe symptoms such as chest pain, visual disturbances, and hearing impairment [1].

Additionally, a 38-year-old male with insulin-dependent diabetes and depression took 350 mg of Yohimbine and developed symptoms such as bradycardia, retrograde amnesia, and chest pain. Nevertheless, these symptoms resolved afterward [1].

Other reported side effects include:

• Mild anxiety
• Increased urination
• Dizziness
• Cold extremities
• Increased heart rate
• Dry mouth
• Headache
• Chest pain

These are some common side effects of Yohimbine that typically resolve after discontinuation of the medication.

What Is Horny Goat Weed?

Horny Goat Weed is an herbal remedy long used to support sexual dysfunctions, particularly erectile dysfunction in males and low libido in females. Additionally, it is employed in supporting other conditions such as osteoporosis, nerve function improvement, and cardiovascular health [2].

Furthermore, Horny Goat Weed is known by various names including Barrenwort, bishop’s hat, epimedium, and yin yang huo. Legend has it that it earned the name "Horny Goat Weed" because goats were observed to be more sexually active after consuming this herb.

How Does Horny Goat Weed Work For Human Health?

The primary active compound in Horny Goat Weed, icariin, works mainly by inhibiting the enzyme phosphodiesterase type 5 (PDE5). PDE5 typically reduces blood flow to the penis. By inhibiting PDE5, icariin improves blood flow to the penis, aiding in achieving and maintaining erections when needed [3].

Moreover, Horny Goat Weed can increase nitric oxide production, which helps dilate blood vessels and further enhances blood flow to the penis, thus improving erectile function effectively.

What Are The Main Benefits Of Horny Goat Weed For Health?

Support method of sexual dysfunctions: It may enhance sexual performance, reduce recovery time between intercourse, and improve sexual desire. For men, it may also help maintain erections during intercourse. A small study on erectile dysfunction found that using Epimedium (Horny Goat Weed) could improve sexual satisfaction more than sildenafil (Viagra) [2].

Another benefit is its role in bone health. A five-year study showed that this herb could reduce postmenopausal bone loss and decrease the risk of fractures [2].
Its anti-inflammatory and antioxidant effects protect the body from free radical damage and reduce inflammation [4].

Regulates menstrual cycles and supports women with irregular menstruation. After menopause, women experience estrogen deficiency, leading to symptoms like hot flashes, vaginal dryness, and decreased libido. Phytoestrogens in Horny Goat Weed may alleviate these symptoms by providing a small amount of estrogen to the body [5].

It improves nerve function, potentially enhancing memory [2].

Has potential cholesterol-lowering and anti-atherosclerotic effects [5].

These are some of the notable benefits of Horny Goat Weed for human health, making it a popular choice in traditional and contemporary herbal medicine.

Read more: Does Horny Goat Weed Work For Women?

Is Horny Goat Weed Safe to Take?

Using Horny Goat Weed may lead to some side effects.

For instance, high doses can cause stimulation, sweating, or feelings of warmth.

Another notable point is that animal studies suggest prolonged overdose may reduce thyroid gland function.

Moreover, a 66-year-old man was reportedly suspected of heart rhythm disturbances and depression after using a libido-enhancing product containing Horny Goat Weed. However, this requires further study for confirmation [2].

Horny Goat Weed may also interact with certain medications, such as:

• Other PDE-5 inhibitors like sildenafil (Viagra).
• Medications for high blood pressure.
• Antiarrhythmic medications.
• Blood thinners.

Combining Horny Goat Weed with sildenafil can reduce the effectiveness of sildenafil.

Not only with sildenafil but when combined with other medications, it's important to note that this herb may inhibit CYP450 enzymes, potentially increasing the risk of drug interactions. However, the extent of its impact still needs to be fully understood.

Can You Combine Yohimbe And Horny Goat Weed Together?

Combining Yohimbe and Horny Goat Weed can lead to high blood pressure and behavioral changes such as anxiety, agitation, and irritability when used in high doses. Therefore, it's advisable to combine these two herbs with professional guidance [6].

Additionally, there are alternative methods to enhance mental well-being, sexual health, and erectile function without using herbs, such as regular exercise, maintaining a balanced diet, and reducing stress, which can yield positive outcomes.

Conclusion

Both Yohimbine and Horny Goat Weed are used to support the method of erectile dysfunction. Yohimbe may be a suitable choice if you are looking for a scientifically validated method. Alternatively, if you prefer a natural solution to support yourself, you might consider Horny Goat Weed. Always listen to your doctor's advice to make the safest and most suitable choice for yourself.

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