Can You Take Serrapeptase And NAC Together

Can You Take Serrapeptase And NAC Together?

Serrapeptase and NAC (N-acetylcysteine) are commonly used supplements to support health.

Although they have been shown to provide clear beneficial results, a question arises regarding combining these two supplements: "Can you use Serrapeptase and NAC together?"

Some believe it's beneficial, while others are skeptical due to the lack of extensive research on this combination. This article aims to address these concerns, so stay tuned below for more insights.


Key Takeaways

  • Serrapeptase is a proteolytic enzyme originating from the bacterium Serratia, with the ability to break down unnecessary proteins in the body, helping reduce inflammation, alleviate pain, and support the body's natural cleansing process.
  • NAC is an acetylated form of the amino acid cysteine, capable of enhancing the production of glutathione - a powerful antioxidant in the body, helping protect cells from damage and eliminate toxins.
  • Many believe that using both supplements can bring numerous health benefits.
  • Serrapeptase and NAC must be carefully monitored in terms of dosage and duration to achieve the best results.

Can You Take Serrapeptase And NAC Together?

Serrapeptase and NAC (N-Acetylcysteine) can be used together

Serrapeptase and NAC (N-Acetylcysteine) can be used together.

Some individuals have reported improvements in their health conditions after using these supplements.

However, this should be discussed with a doctor or healthcare professional to ensure that it is appropriate and safe for your case.

What is NAC, and What are Its Potential Health Benefits?

N-acetylcysteine (NAC) is a drug approved by the FDA and recognized by the WHO, primarily used for treating acetaminophen overdose and as a mucolytic agent in respiratory diseases [1].

NAC enhances glutathione in diseases related to oxidative stress, helping protect cells from cellular damage and reducing inflammation.

Furthermore, NAC has been researched and proven to have many health benefits, including supporting liver function, reducing inflammation, protecting the liver from harmful effects, and alleviating symptoms of respiratory diseases such as bronchitis and pneumonia.

What is Serrapeptase and Its Benefits?

what is serrapeptase

Serrapeptase is a proteolytic enzyme with many beneficial biological properties, such as anti-inflammatory, analgesic, antibacterial, and fibrinolytic [2].

It is widely used to treat various conditions such as arthritis, sore throat, tonsillitis, sinusitis, injuries, and digestive issues.

It is known for reducing inflammation, alleviating pain, and supporting the body's natural processes of bacterial and debris clearance.

Serrapeptase can also aid wound healing and alleviate symptoms of certain inflammatory infections.

Why Are Some People Taking Serrapeptase and NAC Together?

There are several reasons why some people choose to use both Serrapeptase and NAC together. Most of these reasons revolve around the potential health benefits that this combination can provide:

Enhanced Anti-inflammatory Benefits: Both Serrapeptase and NAC have anti-inflammatory properties. When used together, they can complement each other in effectively reducing inflammation throughout the body compared to using them individually.

Respiratory Health Support: NAC is renowned for its mucolytic properties, helping to break down mucus in the lungs and respiratory tract and facilitating easier breathing.

Serrapeptase, on the other hand, may help reduce inflammation in the respiratory tract.

Combining these two supplements can provide comprehensive support for respiratory health, especially in bronchitis or chronic obstructive pulmonary disease (COPD).

Joint Health Support: Serrapeptase often alleviates pain and inflammation associated with joint conditions like arthritis.

With its antioxidant properties, NAC can help protect joint tissue from oxidative stress. Together, they can provide more holistic support for joint health and comfort.

Serrapeptase and NAC have been researched for their potential benefits in promoting overall health and well-being.

They can support various biological processes, including immune function, tissue regeneration, and detoxification.

Using both together may offer multiple health benefits.

How to Take Serrapeptase Safely?

Ways to Take Serrapeptase Safely

When using Serrapeptase, the most important aspect is to adhere to the recommended dosage and monitor the body's response.

When taken orally, stomach acid can destroy and deactivate serrapeptase before it is absorbed into the intestines.

Therefore, serrapeptase supplements should be enteric-coated to prevent them from dissolving in the stomach and facilitate release in the intestines.

Doses typically range from 10 mg to 60 mg per day, measured in enzymatic activity units [3].

Additionally, Serrapeptase should be taken on an empty stomach at least 30 minutes before eating or two hours after finishing a meal.

However, carefully read the product instructions to ensure safety when using Serrapeptase, as some products are designed for specific timing to maximize effectiveness.

How to Take NAC Supplements?

NAC is commonly available in tablets or powder and can be taken in pill form or diluted in water. The appropriate dosage depends on the intended use and the doctor's instructions.

Additionally, NAC can be taken at any time of day that is most convenient. NAC tablets typically come in doses ranging from 500 mg to 1,000 mg.

For faster results when using NAC, it's advisable to divide the dose and take it twice or thrice daily, such as once in the morning and once at night.

It's important to use it regularly and at the correct dosage to ensure the body adapts well to this supplement.


Serrapeptase and NAC are two types of supplements that may have health benefits.

Combining both can offer good health benefits, but further clinical research is required to substantiate its validity.

The article also addresses how to safely use Serrapeptase and NAC, as well as the concept and potential benefits of both. Hopefully, you have found answers to the question of whether Serrapeptase and NAC can be used together or not.


[1] Cristina, Nayara Gomes Graciliano, Fabiana Andréa Moura, Cabral A, Oliveira M. N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants. 2021;10(6):967-967. doi:
[2] Selvarajan Ethiraj, Gopinath S. Production, purification, characterization, immobilization, and application of Serrapeptase: a review. Frontiers in Biology. 2017;12(5):333-348. doi:
‌[3] Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. International journal of surgery. 2013;11(3):209-217. doi:‌
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Ralph S. Albert, with over 10 years of expertise in nutrition and research, now heads the Research division at Vinatura Supplements. His dedication and extensive knowledge ensure top-quality articles on nutrition and health, collaborating with a skilled team. He has successfully completed The VINATURA Expertise Research Training Program, underscoring his commitment to Vinatura's mission. Ralph has also published numerous articles and conducted valuable research in the field, making him a trusted resource for individuals on their wellness journey.

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